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Lamotrigine: Serum lamotrigine concentrations could be decreased, generating a minimize in therapeutic consequences.The subsequent are clinically considerable drug interactions with oxycodone. This isn't an all-inclusive listing — other prescription drugs not mentioned right here might result in an interaction. Major drug interactions consist of:

Oral Contraceptives: Boost in glucuronidation causing enhanced plasma clearance as well as a lowered fifty percent-lifetime of acetaminophen.Following administration of PERCOCET tablets, anaphylactic reactions have already been described in individuals having a regarded hypersensitivity to codeine, a compound which has a construction similar to mor